SMU Mustangs vs Louisville Cardinals Picks and Predictions

SMU Mustangs vs Louisville Cardinals Best Betting Picks

SMU Mustangs
Line: +1.5 Total: o58.5 Score: 0

Louisville Cardinals
Line: -1.5 Total: u58.5 Score: 0

Make your bets before 3:30pm EST 9/19/2026

Best Bets for the SMU Mustangs vs Louisville Cardinals

Below are the top 5 sports handicappers with picks on this game. Experts are listed in order based based on their hit rate from previous picks on the SMU Mustangs and/or Louisville Cardinals games and their overall NCAAF rankings. Visit their website directly to purchase their best bets for the day.

Rank	Sports Handicapper	30 Day NCAAF Record	NCAAF Season Record	Hit Rate	Website
#1	Brian Quincy	13-6 (68%), +$3,260	13-6 (68%), +$3,260	100%	View Website
#2	Scott Allen Stanley	9-4 (69%), +$2,285	9-4 (69%), +$2,285	100%	View Website
#3	Kevin Fitch	20-14 (59%), +$2,245	20-14 (59%), +$2,245	100%	View Website
#4	Brandon Donelly	11-6 (65%), +$2,220	11-6 (65%), +$2,220	100%	View Website
#5	Patrick Adams	10-10 (50%), +$5	10-10 (50%), +$5	100%	View Website

Vegas Trends and Betting Odds

SMU Mustangs have won the past 4 out of 5 games (4 of 5 ATS) while the Louisville Cardinals have won the past 3 out of 5 games (3 of 5 ATS). The SMU Mustangs are 2 and 3 on the most recent away games while the Louisville Cardinals are 3 and 2 at home. Vegas has the line at Louisville Cardinals -1.5 and the total at 58.5.

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