Virginia Tech Hokies vs Louisville Cardinals Picks and Predictions

Virginia Tech Hokies vs Louisville Cardinals Best Betting Picks

Virginia Tech Hokies
Line: +12.5 Total: o159.5 Score: 0

Louisville Cardinals
Line: -12.5 Total: u159.5 Score: 0

Make your bets before 2:15pm EST 1/24/2026

Best Bets for the Virginia Tech Hokies vs Louisville Cardinals

Below are the top 5 sports handicappers with picks on this game. Experts are listed in order based based on their hit rate from previous picks on the Virginia Tech Hokies and/or Louisville Cardinals games and their overall NCAAB rankings. Visit their website directly to purchase their best bets for the day.

Rank	Sports Handicapper	30 Day NCAAB Record	NCAAB Season Record	Hit Rate	Website
#1	Mike Davis	57-30 (66%), +$12,445	147-66 (69%), +$37,380	86%	View Website
#2	Greg Michaels	64-27 (70%), +$17,100	136-66 (67%), +$31,765	80%	View Website
#3	Ryne Bach	44-34 (56%), +$3,365	113-81 (58%), +$12,240	64%	View Website
#4	Matt O'Brien	52-30 (63%), +$9,595	121-79 (61%), +$17,055	54%	View Website
#5	Wes Salvato	59-32 (65%), +$11,830	152-91 (63%), +$25,970	52%	View Website

Vegas Trends and Betting Odds

Virginia Tech Hokies have won the past 3 out of 5 games (3 of 5 ATS) while the Louisville Cardinals have won the past 2 out of 5 games (1 of 5 ATS). The Virginia Tech Hokies are 2 and 3 on the most recent away games while the Louisville Cardinals are 3 and 2 at home. Vegas has the line at Louisville Cardinals -12.5 and the total at 159.5.

More hot bets: Clemson Tigers @ Georgia Tech Yellow Jackets, West Virginia Mountaineers @ Arizona Wildcats, or Florida State Seminoles @ SMU Mustangs.