San Francisco 49ers vs Seattle Seahawks Picks and Predictions

San Francisco 49ers vs Seattle Seahawks Best Betting Picks

San Francisco 49ers
Line: +7 Total: o45.5 Score: 0

Seattle Seahawks
Line: -7 Total: u45.5 Score: 0

Make your bets before 8:00pm EST 1/17/2026

Best Bets for the San Francisco 49ers vs Seattle Seahawks

Below are the top 5 sports handicappers with picks on this game. Experts are listed in order based based on their hit rate from previous picks on the San Francisco 49ers and/or Seattle Seahawks games and their overall NFL rankings. Visit their website directly to purchase their best bets for the day.

Rank	Sports Handicapper	30 Day NFL Record	NFL Season Record	Hit Rate	Website
#1	Trevor J. Bass	22-14 (61%), +$3,540	89-45 (66%), +$20,255	36%	View Website
#2	Wes Salvato	25-15 (63%), +$4,325	105-62 (63%), +$18,305	56%	View Website
#3	Oliver Peters	22-12 (65%), +$4,415	103-61 (63%), +$18,240	0%	View Website
#4	Elon Koebler	19-4 (83%), +$7,315	65-28 (70%), +$17,765	0%	View Website
#5	Brock Lloyd	23-13 (64%), +$4,430	98-59 (62%), +$17,050	0%	View Website

Vegas Trends and Betting Odds

San Francisco 49ers have won the past 4 out of 5 games (3 of 5 ATS) while the Seattle Seahawks have won the past 5 out of 5 games (3 of 5 ATS). The San Francisco 49ers are 5 and 0 on the most recent away games while the Seattle Seahawks are 5 and 0 at home. Vegas has the line at Seattle Seahawks -7 and the total at 45.5.

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