Best Bets for the San Francisco 49ers vs Indianapolis Colts
Below are the top 5 sports handicappers with picks on this game. Experts are listed in order based based on their hit rate from previous picks on the San Francisco 49ers and/or Indianapolis Colts games and their overall NFL rankings. Visit their website directly to purchase their best bets for the day.
Vegas Trends and Betting Odds
San Francisco 49ers have won the past 4 out of 5 games (4 of 5 ATS) while the Indianapolis Colts have won the past 1 out of 5 games (3 of 5 ATS). The San Francisco 49ers are 3 and 2 on the most recent away games while the Indianapolis Colts are 4 and 1 at home. Vegas has the line at San Francisco 49ers -5.5 and the total at 45.5.
More hot bets: Utah Tech Trailblazers @ Creighton Bluejays, Prairie View A&M Panthers @ LSU Tigers, or Orlando Magic @ Golden State Warriors.

