NCAAB Matchups 12/21/2025

View a matchup to see picks from expert NCAAB handicappers.

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Final 4:00 pm EDT — Game is Complete Sunday, December 21, 2025

New Mexico State Aggies is favored -5.5. Total is 153.5.

Last 5: 3/5 (4/5 ATS)
Last 5: 2/5 (2/5 ATS)

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Final 3:00 pm EDT — Game is Complete Sunday, December 21, 2025

Chattanooga Mocs is favored -2.5. Total is 138.5.

Last 5: 1/5 (2/5 ATS)
Last 5: 2/5 (3/5 ATS)

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Final 3:00 pm EDT — Game is Complete Sunday, December 21, 2025

Clemson Tigers is favored -3.5. Total is 140.5.

Last 5: 2/5 (2/5 ATS)
Last 5: 3/5 (2/5 ATS)

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Final 3:00 pm EDT — Game is Complete Sunday, December 21, 2025

Cornell Big Red is favored -6.5. Total is 167.5.

Last 5: 2/5 (2/5 ATS)
Last 5: 1/5 (2/5 ATS)

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Final 3:00 pm EDT — Game is Complete Sunday, December 21, 2025

Saint Louis Billikens is favored -34.5. Total is 157.5.

Last 5: 2/5 (4/5 ATS)
Last 5: 5/5 (3/5 ATS)

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Final 3:00 pm EDT — Game is Complete Sunday, December 21, 2025

Incarnate Word Cardinals is favored -6.5. Total is 140.5.

Last 5: 1/5 (2/5 ATS)
Last 5: 2/5 (3/5 ATS)

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Final 3:00 pm EDT — Game is Complete Sunday, December 21, 2025

Arizona State Sun Devils is favored -12.5. Total is 147.5.

Last 5: 4/5 (4/5 ATS)
Last 5: 3/5 (3/5 ATS)

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Final 3:00 pm EDT — Game is Complete Sunday, December 21, 2025

South Florida Bulls is favored -22.5. Total is 160.5.

Last 5: 1/5 (2/5 ATS)
Last 5: 3/5 (3/5 ATS)

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Final 3:00 pm EDT — Game is Complete Sunday, December 21, 2025

UAB Blazers is favored -12.5. Total is 151.5.

Last 5: 1/5 (2/5 ATS)
Last 5: 3/5 (3/5 ATS)

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Final 2:30 pm EDT — Game is Complete Sunday, December 21, 2025

Radford Highlanders is favored -11.5. Total is 158.5.

Last 5: 1/5 (3/5 ATS)
Last 5: 3/5 (3/5 ATS)

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Final 2:00 pm EDT — Game is Complete Sunday, December 21, 2025

Oklahoma State Cowboys is favored -19.5. Total is 177.5.

Last 5: 2/5 (3/5 ATS)
Last 5: 4/5 (1/5 ATS)

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Final 2:00 pm EDT — Game is Complete Sunday, December 21, 2025

SMU Mustangs is favored -24.5. Total is 156.5.

Last 5: 1/5 (3/5 ATS)
Last 5: 3/5 (1/5 ATS)

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Final 2:00 pm EDT — Game is Complete Sunday, December 21, 2025

Furman Paladins is favored -10.5. Total is 155.5.

Last 5: 3/5 (4/5 ATS)
Last 5: 4/5 (2/5 ATS)

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Final 2:00 pm EDT — Game is Complete Sunday, December 21, 2025

Alabama Crimson Tide is favored -20.5. Total is 182.5.

Last 5: 3/5 (4/5 ATS)
Last 5: 4/5 (1/5 ATS)

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Final 2:00 pm EDT — Game is Complete Sunday, December 21, 2025

George Mason Patriots is favored -23.5. Total is 145.5.

Last 5: 1/5 (2/5 ATS)
Last 5: 4/5 (2/5 ATS)

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Final 2:00 pm EDT — Game is Complete Sunday, December 21, 2025

Drexel Dragons is favored -10.5. Total is 129.5.

Last 5: 1/5 (1/5 ATS)
Last 5: 2/5 (3/5 ATS)

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Final 2:00 pm EDT — Game is Complete Sunday, December 21, 2025

Murray State Racers is favored -5.5. Total is 155.5.

Last 5: 5/5 (4/5 ATS)
Last 5: 1/5 (3/5 ATS)

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Final 2:00 pm EDT — Game is Complete Sunday, December 21, 2025

Presbyterian Blue Hose is favored -1.5. Total is 138.5.

Last 5: 2/5 (2/5 ATS)
Last 5: 2/5 (3/5 ATS)

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Final 2:00 pm EDT — Game is Complete Sunday, December 21, 2025

Notre Dame Fighting Irish is favored -11.5. Total is 149.5.

Last 5: 4/5 (3/5 ATS)
Last 5: 4/5 (4/5 ATS)

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Final 2:00 pm EDT — Game is Complete Sunday, December 21, 2025

Bradley Braves is favored -6.5. Total is 152.5.

Last 5: 2/5 (3/5 ATS)
Last 5: 5/5 (3/5 ATS)

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Final 2:00 pm EDT — Game is Complete Sunday, December 21, 2025

Charlotte 49ers is favored -1.5. Total is 137.5.

Last 5: 0/5 (1/5 ATS)
Last 5: 3/5 (3/5 ATS)

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Final 1:00 pm EDT — Game is Complete Sunday, December 21, 2025

Monmouth Hawks is favored -9.5. Total is 143.5.

Last 5: 1/5 (1/5 ATS)
Last 5: 2/5 (1/5 ATS)

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Final 1:00 pm EDT — Game is Complete Sunday, December 21, 2025

NC State Wolfpack is favored -7.5. Total is 148.5.

Last 5: 2/5 (1/5 ATS)
Last 5: 4/5 (3/5 ATS)

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Final 1:00 pm EDT — Game is Complete Sunday, December 21, 2025

Hofstra Pride is favored -6.5. Total is 147.5.

Last 5: 4/5 (2/5 ATS)
Last 5: 4/5 (5/5 ATS)

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Final 1:00 pm EDT — Game is Complete Sunday, December 21, 2025

Baylor Bears is favored -25.5. Total is 169.5.

Last 5: 1/5 (3/5 ATS)
Last 5: 4/5 (3/5 ATS)

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Final 1:00 pm EDT — Game is Complete Sunday, December 21, 2025

Marist Red Foxes is favored -5.5. Total is 137.5.

Last 5: 2/5 (3/5 ATS)
Last 5: 4/5 (3/5 ATS)

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Final 1:00 pm EDT — Game is Complete Sunday, December 21, 2025

Vanderbilt Commodores is favored -6.5. Total is 164.5.

Last 5: 5/5 (3/5 ATS)
Last 5: 3/5 (2/5 ATS)

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Final 12:00 pm EDT — Game is Complete Sunday, December 21, 2025

Northern Kentucky Norse is favored -4.5. Total is 152.5.

Last 5: 3/5 (3/5 ATS)
Last 5: 2/5 (1/5 ATS)

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Final 12:00 pm EDT — Game is Complete Sunday, December 21, 2025

Florida Gators is favored -27.5. Total is 156.5.

Last 5: 2/5 (3/5 ATS)
Last 5: 3/5 (3/5 ATS)

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Final 12:00 pm EDT — Game is Complete Sunday, December 21, 2025

Penn State Nittany Lions is favored -1.5. Total is 146.5.

Last 5: 3/5 (3/5 ATS)
Last 5: 2/5 (2/5 ATS)

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