MLB Matchups 9/22/2026

View a matchup to see picks from expert MLB handicappers.

Final 9:40 pm EDT — Game is Complete Tuesday, September 22, 2026

Los Angeles Angels is favored -109. Total is 9.5.

Last 5: 1/5
Last 5: /5

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Final 8:40 pm EDT — Game is Complete Tuesday, September 22, 2026

Arizona Diamondbacks is favored -181. Total is 11.

Last 5: 5/5
Last 5: 1/5

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Final 8:05 pm EDT — Game is Complete Tuesday, September 22, 2026

Texas Rangers is favored -126. Total is 8.5.

Last 5: 3/5
Last 5: 2/5

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Final 7:40 pm EDT — Game is Complete Tuesday, September 22, 2026

Chicago White Sox is favored -125. Total is 8.

Last 5: 4/5
Last 5: 1/5

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Final 7:40 pm EDT — Game is Complete Tuesday, September 22, 2026

Chicago Cubs is favored -217. Total is 6.5.

Last 5: 2/5
Last 5: 3/5

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Final 7:15 pm EDT — Game is Complete Tuesday, September 22, 2026

Atlanta Braves is favored -238. Total is 9.5.

Last 5: 2/5
Last 5: 3/5

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Final 7:05 pm EDT — Game is Complete Tuesday, September 22, 2026

New York Yankees is favored -130. Total is 6.

Last 5: 2/5
Last 5: 3/5

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Final 6:45 pm EDT — Game is Complete Tuesday, September 22, 2026

Boston Red Sox is favored -125. Total is 6.

Last 5: 4/5
Last 5: 1/5

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Final 6:40 pm EDT — Game is Complete Tuesday, September 22, 2026

Philadelphia Phillies is favored -155. Total is 7.

Last 5: 4/5
Last 5: 2/5

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Final 6:40 pm EDT — Game is Complete Tuesday, September 22, 2026

Pittsburgh Pirates is favored -169. Total is 7.

Last 5: 2/5
Last 5: 4/5

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Final 6:40 pm EDT — Game is Complete Tuesday, September 22, 2026

Detroit Tigers is favored -150. Total is 8.

Last 5: 3/5
Last 5: 1/5

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Cancelled 6:35 pm EDT — Game is Complete Tuesday, September 22, 2026

Baltimore Orioles is favored -123. Total is 7.

Last 5: 1/5
Last 5: 3/5

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Final 1:05 pm EDT — Game is Complete Tuesday, September 22, 2026

New York Yankees is favored -149. Total is 6.5.

Last 5: 2/5
Last 5: 3/5

NFL Matchups 9/21/2026

View a matchup to see picks from expert NFL handicappers.

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Final 8:15 pm EDT — Game is Complete Monday, September 21, 2026

Los Angeles Rams is favored -6.5. Total is 47.5.

Last 5: 4/5 (4/5 ATS)
Last 5: 3/5 (3/5 ATS)

MLB Matchups 9/21/2026

View a matchup to see picks from expert MLB handicappers.

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Final 9:45 pm EDT — Game is Complete Monday, September 21, 2026

Minnesota Twins is favored -132. Total is 8.

Last 5: 3/5
Last 5: 1/5

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Final 6:40 pm EDT — Game is Complete Monday, September 21, 2026

Detroit Tigers is favored -133. Total is 8.5.

Last 5: 3/5
Last 5: 1/5

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Final 6:35 pm EDT — Game is Complete Monday, September 21, 2026

Toronto Blue Jays is favored -110. Total is 7.5.

Last 5: 1/5
Last 5: 3/5

NFL Matchups 9/20/2026

View a matchup to see picks from expert NFL handicappers.

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Final 8:20 pm EDT — Game is Complete Sunday, September 20, 2026

Kansas City Chiefs is favored -6. Total is 46.5.

Last 5: 0/5 (1/5 ATS)
Last 5: 1/5 (3/5 ATS)

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Final 4:25 pm EDT — Game is Complete Sunday, September 20, 2026

San Francisco 49ers is favored -12.5. Total is 44.5.

Last 5: 0/5 (0/5 ATS)
Last 5: 4/5 (5/5 ATS)

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Final 4:25 pm EDT — Game is Complete Sunday, September 20, 2026

Seattle Seahawks is favored -3.5. Total is 40.5.

Last 5: 2/5 (2/5 ATS)
Last 5: 2/5 (2/5 ATS)

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Final 4:25 pm EDT — Game is Complete Sunday, September 20, 2026

Dallas Cowboys is favored -3.5. Total is 51.5.

Last 5: 1/5 (3/5 ATS)
Last 5: 3/5 (3/5 ATS)

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Final 4:05 pm EDT — Game is Complete Sunday, September 20, 2026

Denver Broncos is favored -2.5. Total is 45.5.

Last 5: 3/5 (3/5 ATS)
Last 5: 3/5 (3/5 ATS)

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Final 4:05 pm EDT — Game is Complete Sunday, September 20, 2026

Los Angeles Chargers is favored -6.5. Total is 43.5.

Last 5: 3/5 (3/5 ATS)
Last 5: 1/5 (1/5 ATS)

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Final 1:00 pm EDT — Game is Complete Sunday, September 20, 2026

Carolina Panthers is favored -2.5. Total is 43.5.

Last 5: 3/5 (3/5 ATS)
Last 5: 2/5 (2/5 ATS)

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Final 1:00 pm EDT — Game is Complete Sunday, September 20, 2026

Houston Texans is favored -3. Total is 45.5.

Last 5: 5/5 (4/5 ATS)
Last 5: 0/5 (0/5 ATS)

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Final 1:00 pm EDT — Game is Complete Sunday, September 20, 2026

Tampa Bay Buccaneers is favored -8.5. Total is 41.5.

Last 5: 2/5 (2/5 ATS)
Last 5: 2/5 (1/5 ATS)

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Final 1:00 pm EDT — Game is Complete Sunday, September 20, 2026

Green Bay Packers is favored -3.5. Total is 44.5.

Last 5: 3/5 (2/5 ATS)
Last 5: 2/5 (3/5 ATS)

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Final 1:00 pm EDT — Game is Complete Sunday, September 20, 2026

Chicago Bears is favored -4.5. Total is 46.5.

Last 5: 3/5 (3/5 ATS)
Last 5: 3/5 (3/5 ATS)

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Final 1:00 pm EDT — Game is Complete Sunday, September 20, 2026

Baltimore Ravens is favored -8.5. Total is 45.5.

Last 5: 2/5 (3/5 ATS)
Last 5: 4/5 (4/5 ATS)

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Final 1:00 pm EDT — Game is Complete Sunday, September 20, 2026

Philadelphia Eagles is favored -7. Total is 39.5.

Last 5: 2/5 (0/5 ATS)
Last 5: 2/5 (1/5 ATS)

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