NCAAF Matchups 10/4/2025

View a matchup to see picks from expert NCAAF handicappers.

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Open 5:00 pm EDT — Game is Complete Saturday, October 4, 2025

Montana State Bobcats is favored -7.5. Total is 59.5.

Last 5: 2/5 (3/5 ATS)
Last 5: 2/5 (2/5 ATS)

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Final 4:00 pm EDT — Game is Complete Saturday, October 4, 2025

Oklahoma Sooners is favored -46.5. Total is 54.5.

Last 5: 2/5 (3/5 ATS)
Last 5: 3/5 (2/5 ATS)

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Final 4:00 pm EDT — Game is Complete Saturday, October 4, 2025

Nebraska Cornhuskers is favored -12.5. Total is 49.5.

Last 5: 1/5 (3/5 ATS)
Last 5: 3/5 (1/5 ATS)

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Final 4:00 pm EDT — Game is Complete Saturday, October 4, 2025

Texas State Bobcats is favored -14.5. Total is 63.5.

Last 5: 1/5 (1/5 ATS)
Last 5: 3/5 (3/5 ATS)

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Final 3:30 pm EDT — Game is Complete Saturday, October 4, 2025

Notre Dame Fighting Irish is favored -21.5. Total is 63.5.

Last 5: 4/5 (4/5 ATS)
Last 5: 4/5 (3/5 ATS)

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Final 3:30 pm EDT — Game is Complete Saturday, October 4, 2025

Central Michigan Chippewas is favored -7.5. Total is 47.5.

Last 5: 3/5 (3/5 ATS)
Last 5: 2/5 (2/5 ATS)

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Final 3:30 pm EDT — Game is Complete Saturday, October 4, 2025

Buffalo Bulls is favored -9.5. Total is 53.5.

Last 5: 1/5 (3/5 ATS)
Last 5: 2/5 (0/5 ATS)

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Final 3:30 pm EDT — Game is Complete Saturday, October 4, 2025

UConn Huskies is favored -6.5. Total is 51.5.

Last 5: 2/5 (2/5 ATS)
Last 5: 4/5 (3/5 ATS)

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Final 3:30 pm EDT — Game is Complete Saturday, October 4, 2025

James Madison Dukes is favored -18.5. Total is 52.5.

Last 5: 5/5 (3/5 ATS)
Last 5: 0/5 (1/5 ATS)

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Final 3:30 pm EDT — Game is Complete Saturday, October 4, 2025

Miami (OH) RedHawks is favored -4.5. Total is 39.5.

Last 5: 5/5 (5/5 ATS)
Last 5: 1/5 (1/5 ATS)

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Final 3:30 pm EDT — Game is Complete Saturday, October 4, 2025

App State Mountaineers is favored -1.5. Total is 53.5.

Last 5: 0/5 (0/5 ATS)
Last 5: 2/5 (3/5 ATS)

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Final 3:30 pm EDT — Game is Complete Saturday, October 4, 2025

Penn State Nittany Lions is favored -25.5. Total is 47.5.

Last 5: 1/5 (1/5 ATS)
Last 5: 3/5 (3/5 ATS)

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Final 3:30 pm EDT — Game is Complete Saturday, October 4, 2025

SMU Mustangs is favored -18.5. Total is 56.5.

Last 5: 1/5 (2/5 ATS)
Last 5: 3/5 (2/5 ATS)

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Final 3:30 pm EDT — Game is Complete Saturday, October 4, 2025

Texas Longhorns is favored -5.5. Total is 42.5.

Last 5: 4/5 (2/5 ATS)
Last 5: 2/5 (1/5 ATS)

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Final 3:30 pm EDT — Game is Complete Saturday, October 4, 2025

Northwestern Wildcats is favored -13.5. Total is 43.5.

Last 5: 1/5 (1/5 ATS)
Last 5: 4/5 (3/5 ATS)

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Final 3:30 pm EDT — Game is Complete Saturday, October 4, 2025

Alabama Crimson Tide is favored -13.5. Total is 57.5.

Last 5: 4/5 (3/5 ATS)
Last 5: 5/5 (3/5 ATS)

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Final 3:30 pm EDT — Game is Complete Saturday, October 4, 2025

Louisville Cardinals is favored -6.5. Total is 60.5.

Last 5: 5/5 (3/5 ATS)
Last 5: 4/5 (2/5 ATS)

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Final 3:30 pm EDT — Game is Complete Saturday, October 4, 2025

Washington Huskies is favored -5.5. Total is 52.5.

Last 5: 3/5 (2/5 ATS)
Last 5: 3/5 (4/5 ATS)

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Final 3:00 pm EDT — Game is Complete Saturday, October 4, 2025

Arizona Wildcats is favored -21.5. Total is 56.5.

Last 5: 0/5 (1/5 ATS)
Last 5: 2/5 (2/5 ATS)

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Final 2:30 pm EDT — Game is Complete Saturday, October 4, 2025

Western Michigan Broncos is favored -12.5. Total is 45.5.

Last 5: 4/5 (4/5 ATS)
Last 5: 0/5 (2/5 ATS)

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Final 1:00 pm EDT — Game is Complete Saturday, October 4, 2025

UTSA Roadrunners is favored -6.5. Total is 57.5.

Last 5: 2/5 (1/5 ATS)
Last 5: 3/5 (4/5 ATS)

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Final 1:00 pm EDT — Game is Complete Saturday, October 4, 2025

Virginia Tech Hokies is favored -4.5. Total is 51.5.

Last 5: 3/5 (4/5 ATS)
Last 5: 1/5 (1/5 ATS)

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Open 12:30 pm EDT — Game is Complete Saturday, October 4, 2025

Lafayette Leopards is favored -15.5. Total is 55.5.

Last 5: 2/5 (2/5 ATS)
Last 5: 0/5 (3/5 ATS)

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Final 12:00 pm EDT — Game is Complete Saturday, October 4, 2025

Navy Midshipmen is favored -13.5. Total is 51.5.

Last 5: 1/5 (2/5 ATS)
Last 5: 5/5 (1/5 ATS)

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Final 12:00 pm EDT — Game is Complete Saturday, October 4, 2025

Army Black Knights is favored -6.5. Total is 55.5.

Last 5: 2/5 (2/5 ATS)
Last 5: 2/5 (2/5 ATS)

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Final 12:00 pm EDT — Game is Complete Saturday, October 4, 2025

Pittsburgh Panthers is favored -6.5. Total is 54.5.

Last 5: 0/5 (1/5 ATS)
Last 5: 4/5 (4/5 ATS)

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Final 12:00 pm EDT — Game is Complete Saturday, October 4, 2025

Clemson Tigers is favored -15.5. Total is 47.5.

Last 5: 2/5 (2/5 ATS)
Last 5: 1/5 (2/5 ATS)

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Final 12:00 pm EDT — Game is Complete Saturday, October 4, 2025

Illinois Fighting Illini is favored -7.5. Total is 54.5.

Last 5: 2/5 (2/5 ATS)
Last 5: 0/5 (1/5 ATS)

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Final 12:00 pm EDT — Game is Complete Saturday, October 4, 2025

Cincinnati Bearcats is favored -1.5. Total is 55.5.

Last 5: 2/5 (1/5 ATS)
Last 5: 5/5 (4/5 ATS)

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Final 12:00 pm EDT — Game is Complete Saturday, October 4, 2025

Baylor Bears is favored -4.5. Total is 60.5.

Last 5: 3/5 (4/5 ATS)
Last 5: 2/5 (0/5 ATS)

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