NFL Matchups 9/22/2024

View a matchup to see picks from expert NFL handicappers.

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Final 4:25 pm EDT — Game is Complete Sunday, September 22, 2024

San Francisco is favored -4. Total is 46.5.

Last 5: 1/5 (1/5 ATS)
Last 5: 3/5 (4/5 ATS)

vs

Final 4:05 pm EDT — Game is Complete Sunday, September 22, 2024

Las Vegas is favored -4. Total is 43.5.

Last 5: 2/5 (3/5 ATS)
Last 5: 2/5 (3/5 ATS)

vs

Final 4:05 pm EDT — Game is Complete Sunday, September 22, 2024

Miami is favored -2.5. Total is 48.5.

Last 5: 3/5 (2/5 ATS)
Last 5: 3/5 (1/5 ATS)

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Final 1:00 pm EDT — Game is Complete Sunday, September 22, 2024

Indianapolis is favored -1. Total is 46.5.

Last 5: 1/5 (2/5 ATS)
Last 5: 3/5 (1/5 ATS)

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Final 1:00 pm EDT — Game is Complete Sunday, September 22, 2024

Tampa Bay is favored -3.5. Total is 42.5.

Last 5: 2/5 (2/5 ATS)
Last 5: 4/5 (3/5 ATS)

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Final 1:00 pm EDT — Game is Complete Sunday, September 22, 2024

Green Bay is favored -4. Total is 44.5.

Last 5: 2/5 (2/5 ATS)
Last 5: 0/5 (0/5 ATS)

vs

Final 1:00 pm EDT — Game is Complete Sunday, September 22, 2024

Houston is favored -4. Total is 47.

Last 5: 2/5 (3/5 ATS)
Last 5: 4/5 (4/5 ATS)

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Final 1:00 pm EDT — Game is Complete Sunday, September 22, 2024

Pittsburgh is favored -1.5. Total is 43.5.

Last 5: 3/5 (3/5 ATS)
Last 5: 1/5 (2/5 ATS)

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Final 1:00 pm EDT — Game is Complete Sunday, September 22, 2024

Cleveland is favored -6.5. Total is 42.5.

Last 5: 1/5 (2/5 ATS)
Last 5: 0/5 (0/5 ATS)

vs

Final 1:00 pm EDT — Game is Complete Sunday, September 22, 2024

Philadelphia is favored -3. Total is 45.5.

Last 5: 5/5 (4/5 ATS)
Last 5: 1/5 (2/5 ATS)

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