NCAAF Matchups 9/27/2025

View a matchup to see picks from expert NCAAF handicappers.

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Final 10:15 pm EDT — Game is Complete Saturday, September 27, 2025

BYU Cougars is favored -6.5. Total is 48.5.

Last 5: 5/5 (3/5 ATS)
Last 5: 3/5 (3/5 ATS)

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Final 9:00 pm EDT — Game is Complete Saturday, September 27, 2025

Louisiana Tech Bulldogs is favored -4.5. Total is 48.5.

Last 5: 3/5 (4/5 ATS)
Last 5: 1/5 (3/5 ATS)

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Final 8:00 pm EDT — Game is Complete Saturday, September 27, 2025

Marshall Thundering Herd is favored -2.5. Total is 47.5.

Last 5: 4/5 (5/5 ATS)
Last 5: 0/5 (0/5 ATS)

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Final 7:45 pm EDT — Game is Complete Saturday, September 27, 2025

South Carolina Gamecocks is favored -6.5. Total is 47.5.

Last 5: 2/5 (1/5 ATS)
Last 5: 2/5 (3/5 ATS)

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Final 7:30 pm EDT — Game is Complete Saturday, September 27, 2025

Georgia Bulldogs is favored -1.5. Total is 54.5.

Last 5: 4/5 (4/5 ATS)
Last 5: 3/5 (1/5 ATS)

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Final 7:30 pm EDT — Game is Complete Saturday, September 27, 2025

Boise State Broncos is favored -17.5. Total is 59.5.

Last 5: 2/5 (2/5 ATS)
Last 5: 2/5 (3/5 ATS)

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Final 7:30 pm EDT — Game is Complete Saturday, September 27, 2025

Missouri Tigers is favored -44.5. Total is 56.5.

Last 5: 0/5 (2/5 ATS)
Last 5: 5/5 (3/5 ATS)

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Final 7:30 pm EDT — Game is Complete Saturday, September 27, 2025

Penn State Nittany Lions is favored -4.5. Total is 53.5.

Last 5: 4/5 (3/5 ATS)
Last 5: 2/5 (0/5 ATS)

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Final 7:30 pm EDT — Game is Complete Saturday, September 27, 2025

Stanford Cardinal is favored -3.5. Total is 49.5.

Last 5: 1/5 (3/5 ATS)
Last 5: 1/5 (0/5 ATS)

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Final 7:30 pm EDT — Game is Complete Saturday, September 27, 2025

Colorado State Rams is favored -6.5. Total is 48.5.

Last 5: 1/5 (2/5 ATS)
Last 5: 0/5 (2/5 ATS)

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Final 7:00 pm EDT — Game is Complete Saturday, September 27, 2025

Iowa State Cyclones is favored -4.5. Total is 48.5.

Last 5: 3/5 (3/5 ATS)
Last 5: 4/5 (3/5 ATS)

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Final 7:00 pm EDT — Game is Complete Saturday, September 27, 2025

Southern Miss Golden Eagles is favored -5.5. Total is 56.5.

Last 5: 1/5 (3/5 ATS)
Last 5: 2/5 (2/5 ATS)

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Final 7:00 pm EDT — Game is Complete Saturday, September 27, 2025

Memphis Tigers is favored -13.5. Total is 62.5.

Last 5: 5/5 (5/5 ATS)
Last 5: 2/5 (2/5 ATS)

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Final 7:00 pm EDT — Game is Complete Saturday, September 27, 2025

NC State Wolfpack is favored -10.5. Total is 56.5.

Last 5: 1/5 (1/5 ATS)
Last 5: 3/5 (3/5 ATS)

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Final 7:00 pm EDT — Game is Complete Saturday, September 27, 2025

Western Kentucky Hilltoppers is favored -4.5. Total is 58.5.

Last 5: 4/5 (4/5 ATS)
Last 5: 0/5 (2/5 ATS)

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Final 6:00 pm EDT — Game is Complete Saturday, September 27, 2025

Old Dominion Monarchs is favored -14.5. Total is 53.5.

Last 5: 0/5 (1/5 ATS)
Last 5: 4/5 (4/5 ATS)

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Final 6:00 pm EDT — Game is Complete Saturday, September 27, 2025

Kennesaw State Owls is favored -6.5. Total is 54.5.

Last 5: 1/5 (1/5 ATS)
Last 5: 3/5 (4/5 ATS)

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Final 4:15 pm EDT — Game is Complete Saturday, September 27, 2025

Tennessee Volunteers is favored -7.5. Total is 63.5.

Last 5: 3/5 (2/5 ATS)
Last 5: 3/5 (3/5 ATS)

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Final 4:00 pm EDT — Game is Complete Saturday, September 27, 2025

New Mexico Lobos is favored -16.5. Total is 52.5.

Last 5: 2/5 (2/5 ATS)
Last 5: 3/5 (4/5 ATS)

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Final 4:00 pm EDT — Game is Complete Saturday, September 27, 2025

Tulane Green Wave is favored -14.5. Total is 52.5.

Last 5: 4/5 (3/5 ATS)
Last 5: 1/5 (1/5 ATS)

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Final 3:30 pm EDT — Game is Complete Saturday, September 27, 2025

Toledo Rockets is favored -22.5. Total is 49.5.

Last 5: 1/5 (2/5 ATS)
Last 5: 2/5 (3/5 ATS)

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Final 3:30 pm EDT — Game is Complete Saturday, September 27, 2025

Texas A&M Aggies is favored -6.5. Total is 51.5.

Last 5: 3/5 (2/5 ATS)
Last 5: 5/5 (2/5 ATS)

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Final 3:30 pm EDT — Game is Complete Saturday, September 27, 2025

Baylor Bears is favored -20.5. Total is 59.5.

Last 5: 3/5 (1/5 ATS)
Last 5: 0/5 (1/5 ATS)

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Final 3:30 pm EDT — Game is Complete Saturday, September 27, 2025

Boston College Eagles is favored -6.5. Total is 54.5.

Last 5: 3/5 (3/5 ATS)
Last 5: 0/5 (2/5 ATS)

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Final 3:30 pm EDT — Game is Complete Saturday, September 27, 2025

Indiana Hoosiers is favored -8.5. Total is 47.5.

Last 5: 4/5 (2/5 ATS)
Last 5: 2/5 (3/5 ATS)

Final 3:30 pm EDT — Game is Complete Saturday, September 27, 2025

Miami (OH) RedHawks is favored -21.5. Total is 48.5.

Last 5: /5 (/5 ATS)
Last 5: 2/5 (3/5 ATS)

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Final 3:30 pm EDT — Game is Complete Saturday, September 27, 2025

Ole Miss Rebels is favored -3.5. Total is 58.5.

Last 5: 4/5 (3/5 ATS)
Last 5: 5/5 (3/5 ATS)

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Final 3:30 pm EDT — Game is Complete Saturday, September 27, 2025

Ohio State Buckeyes is favored -9.5. Total is 52.5.

Last 5: 5/5 (4/5 ATS)
Last 5: 3/5 (1/5 ATS)

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Final 3:30 pm EDT — Game is Complete Saturday, September 27, 2025

Navy Midshipmen is favored -13.5. Total is 46.5.

Last 5: 2/5 (3/5 ATS)
Last 5: 5/5 (1/5 ATS)

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Final 3:30 pm EDT — Game is Complete Saturday, September 27, 2025

San Diego State Aztecs is favored -1.5. Total is 42.5.

Last 5: 2/5 (2/5 ATS)
Last 5: 1/5 (2/5 ATS)

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