Notre Dame Fighting Irish vs Louisville Cardinals Picks and Predictions

Notre Dame Fighting Irish vs Louisville Cardinals Best Betting Picks

Notre Dame Fighting Irish
Line: +17.5 Total: o154.5 Score: 0

Louisville Cardinals
Line: -17.5 Total: u154.5 Score: 0

Make your bets before 7:00pm EST 2/4/2026

Best Bets for the Notre Dame Fighting Irish vs Louisville Cardinals

Below are the top 5 sports handicappers with picks on this game. Experts are listed in order based based on their hit rate from previous picks on the Notre Dame Fighting Irish and/or Louisville Cardinals games and their overall NCAAB rankings. Visit their website directly to purchase their best bets for the day.

Rank	Sports Handicapper	30 Day NCAAB Record	NCAAB Season Record	Hit Rate	Website
#1	Vincent Moretti	63-23 (73%), +$18,860	149-68 (69%), +$37,100	86%	View Website
#2	Greg Michaels	65-32 (67%), +$14,980	158-78 (67%), +$36,295	76%	View Website
#3	Riley Peterson	64-28 (70%), +$16,670	164-72 (69%), +$42,425	75%	View Website
#4	PJ Breid	53-40 (57%), +$4,575	143-90 (61%), +$22,190	75%	View Website
#5	Puss Williamson	51-49 (51%), -$1,610	129-123 (51%), -$3,055	73%	View Website

Vegas Trends and Betting Odds

Notre Dame Fighting Irish have won the past 1 out of 5 games (1 of 5 ATS) while the Louisville Cardinals have won the past 3 out of 5 games (2 of 5 ATS). The Notre Dame Fighting Irish are 1 and 4 on the most recent away games while the Louisville Cardinals are 3 and 2 at home. Vegas has the line at Louisville Cardinals -17.5 and the total at 154.5.

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