San Francisco 49ers vs Seattle Seahawks Picks and Predictions

San Francisco 49ers vs Seattle Seahawks Best Betting Picks

San Francisco 49ers
Line: +7 Total: o45.5 Score: 0

Seattle Seahawks
Line: -7 Total: u45.5 Score: 0

Make your bets before 8:00pm EST 1/17/2026

Best Bets for the San Francisco 49ers vs Seattle Seahawks

Below are the top 5 sports handicappers with picks on this game. Experts are listed in order based based on their hit rate from previous picks on the San Francisco 49ers and/or Seattle Seahawks games and their overall NFL rankings. Visit their website directly to purchase their best bets for the day.

Rank	Sports Handicapper	30 Day NFL Record	NFL Season Record	Hit Rate	Website
#1	Toby Blair	13-9 (59%), +$1,610	61-43 (59%), +$6,780	100%	View Website
#2	Mike Dolan	7-13 (35%), -$3,565	64-48 (57%), +$5,660	89%	View Website
#3	Greg Michaels	9-10 (47%), -$895	48-44 (52%), +$60	88%	View Website
#4	Vincent Moretti	9-6 (60%), +$1,280	41-29 (59%), +$5,100	85%	View Website
#5	Jimmy Eastman	21-17 (55%), +$1,160	73-65 (53%), -$7,675	80%	View Website

Vegas Trends and Betting Odds

San Francisco 49ers have won the past 4 out of 5 games (3 of 5 ATS) while the Seattle Seahawks have won the past 5 out of 5 games (3 of 5 ATS). The San Francisco 49ers are 5 and 0 on the most recent away games while the Seattle Seahawks are 5 and 0 at home. Vegas has the line at Seattle Seahawks -7 and the total at 45.5.

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