Iowa State Cyclones vs Purdue Boilermakers Picks and Predictions

Iowa State Cyclones vs Purdue Boilermakers Best Betting Picks

Iowa State Cyclones
Line: +5.5 Total: o153.5 Score: 0

Purdue Boilermakers
Line: -5.5 Total: u153.5 Score: 0

Make your bets before 12:00pm EST 12/6/2025

Best Bets for the Iowa State Cyclones vs Purdue Boilermakers

Below are the top 5 sports handicappers with picks on this game. Experts are listed in order based based on their hit rate from previous picks on the Iowa State Cyclones and/or Purdue Boilermakers games and their overall NCAAB rankings. Visit their website directly to purchase their best bets for the day.

Rank	Sports Handicapper	30 Day NCAAB Record	NCAAB Season Record	Hit Rate	Website
#1	James Murphy	66-26 (72%), +$18,340	70-28 (71%), +$19,240	67%	View Website
#2	Jon McFadden	58-18 (76%), +$19,035	62-22 (74%), +$18,810	89%	View Website
#3	Joe Johnson	49-20 (71%), +$13,575	53-22 (71%), +$14,500	40%	View Website
#4	Donny Pearson	55-21 (72%), +$15,895	56-25 (69%), +$14,145	60%	View Website
#5	George Hampton	54-29 (65%), +$11,000	57-32 (64%), +$10,750	57%	View Website

Vegas Trends and Betting Odds

Iowa State Cyclones have won the past 3 out of 5 games (3 of 5 ATS) while the Purdue Boilermakers have won the past 5 out of 5 games (3 of 5 ATS). The Iowa State Cyclones are 1 and 4 on the most recent away games while the Purdue Boilermakers are 5 and 0 at home. Vegas has the line at Purdue Boilermakers -5.5 and the total at 153.5.

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