Syracuse Orange vs Notre Dame Fighting Irish Picks and Predictions

Syracuse Orange vs Notre Dame Fighting Irish Best Betting Picks

Syracuse Orange
Line: +36.5 Total: o50.5 Score: 0

Notre Dame Fighting Irish
Line: -36.5 Total: u50.5 Score: 0

Make your bets before 3:30pm EST 11/22/2025

Best Bets for the Syracuse Orange vs Notre Dame Fighting Irish

Below are the top 5 sports handicappers with picks on this game. Experts are listed in order based based on their hit rate from previous picks on the Syracuse Orange and/or Notre Dame Fighting Irish games and their overall NCAAF rankings. Visit their website directly to purchase their best bets for the day.

Rank	Sports Handicapper	30 Day NCAAF Record	NCAAF Season Record	Hit Rate	Website
#1	Riley Peterson	36-13 (73%), +$10,850	63-41 (61%), -$39,605	78%	View Website
#2	Ethan Alexander	26-10 (72%), +$7,525	54-40 (57%), -$84,185	75%	View Website
#3	Ronald Manney	24-10 (71%), +$6,525	53-41 (56%), +$4,095	86%	View Website
#4	Dave Little	26-12 (68%), +$6,450	55-41 (57%), -$27,308	0%	View Website
#5	Luca Freaman	32-19 (63%), +$5,625	73-57 (56%), +$5,140	0%	View Website

Vegas Trends and Betting Odds

Syracuse Orange have won the past 0 out of 5 games (2 of 5 ATS) while the Notre Dame Fighting Irish have won the past 5 out of 5 games (3 of 5 ATS). The Syracuse Orange are 1 and 4 on the most recent away games while the Notre Dame Fighting Irish are 5 and 0 at home. Vegas has the line at Notre Dame Fighting Irish -36.5 and the total at 50.5.

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