Syracuse Orange vs Notre Dame Fighting Irish Picks and Predictions

Syracuse Orange vs Notre Dame Fighting Irish Best Betting Picks

Syracuse Orange
Line: +36.5 Total: o50.5 Score: 0

Notre Dame Fighting Irish
Line: -36.5 Total: u50.5 Score: 0

Make your bets before 3:30pm EST 11/22/2025

Best Bets for the Syracuse Orange vs Notre Dame Fighting Irish

Below are the top 5 sports handicappers with picks on this game. Experts are listed in order based based on their hit rate from previous picks on the Syracuse Orange and/or Notre Dame Fighting Irish games and their overall NCAAF rankings. Visit their website directly to purchase their best bets for the day.

Rank	Sports Handicapper	30 Day NCAAF Record	NCAAF Season Record	Hit Rate	Website
#1	Scott Allen Stanley	32-26 (55%), +$1,440	81-61 (57%), +$6,820	0%	View Website
#2	Luca Freaman	32-19 (63%), +$5,625	73-57 (56%), +$5,140	0%	View Website
#3	Pepper Shannon	18-20 (47%), -$1,875	55-42 (57%), +$4,620	0%	View Website
#4	Ronald Manney	24-10 (71%), +$6,525	53-41 (56%), +$4,095	86%	View Website
#5	David Luang	17-12 (59%), +$1,975	46-35 (57%), +$3,635	40%	View Website

Vegas Trends and Betting Odds

Syracuse Orange have won the past 0 out of 5 games (2 of 5 ATS) while the Notre Dame Fighting Irish have won the past 5 out of 5 games (3 of 5 ATS). The Syracuse Orange are 1 and 4 on the most recent away games while the Notre Dame Fighting Irish are 5 and 0 at home. Vegas has the line at Notre Dame Fighting Irish -36.5 and the total at 50.5.

More hot bets: UC Santa Barbara Gauchos @ Nevada Wolf Pack, Michigan Wolverines @ Maryland Terrapins, or Rutgers Scarlet Knights @ Ohio State Buckeyes.