Best Bets for the San Francisco vs Buffalo
Below are the top 5 sports handicappers with picks on this game. Experts are listed in order based based on their hit rate from previous picks on the San Francisco and/or Buffalo games and their overall NFL rankings. Visit their website directly to purchase their best bets for the day.
| Rank | Sports Handicapper | Pick | Result | Hit Rate | Website |
|---|---|---|---|---|---|
| #1 | Tyler Samuels | -6 (-110) | Win (+500) | 94% | View Website |
| #2 | Vincent Moretti | Under 44.5 (-110) | Loss (-550) | 83% | View Website |
| #3 | Nathan Powers | Over 44.5 (-110) | Win (+500) | 82% | View Website |
| #4 | Carmine Luzetti | +6 (-105) | Loss (-525) | 78% | View Website |
| #5 | Cameron Owens | Under 44.5 (-110) | Loss (-550) | 54% | View Website |
Vegas Trends and Betting Odds
San Francisco have won the past 4 out of 5 games (4 of 5 ATS) while the Buffalo have won the past 4 out of 5 games (3 of 5 ATS). The San Francisco are 3 and 2 on the most recent away games while the Buffalo are 4 and 1 at home. Vegas has the line at Buffalo -6.5 and the total at 44.5.
More hot bets: New York Jets @ Jacksonville Jaguars, Baltimore Ravens @ Cincinnati Bengals, or Tennessee Titans @ San Francisco 49ers.

