Today's MLB Matchups

View a matchup to see picks from expert MLB handicappers.

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Open 1:05 pm EDT Tuesday, September 22, 2026

New York Yankees is favored -126. Total is 7.

Last 5: 4/5
Last 5: 2/5

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Open 6:35 pm EDT Tuesday, September 22, 2026

Baltimore Orioles is favored -122. Total is 7.5.

Last 5: 2/5
Last 5: 2/5

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Open 6:40 pm EDT Tuesday, September 22, 2026

Philadelphia Phillies is favored -137. Total is 7.

Last 5: 4/5
Last 5: 3/5

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Open 6:40 pm EDT Tuesday, September 22, 2026

Pittsburgh Pirates is favored -155. Total is 7.

Last 5: 1/5
Last 5: 4/5

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Open 6:40 pm EDT Tuesday, September 22, 2026

Detroit Tigers is favored -157. Total is 8.

Last 5: 2/5
Last 5: 2/5

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Open 6:45 pm EDT Tuesday, September 22, 2026

Boston Red Sox is favored -131. Total is 6.5.

Last 5: 5/5
Last 5: 2/5

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Open 7:05 pm EDT Tuesday, September 22, 2026

New York Yankees is favored -132. Total is 6.5.

Last 5: 4/5
Last 5: 2/5

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Open 7:15 pm EDT Tuesday, September 22, 2026

Atlanta Braves is favored -193. Total is 9.5.

Last 5: 2/5
Last 5: 4/5

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Open 7:40 pm EDT Tuesday, September 22, 2026

Chicago White Sox is favored -120. Total is 8.

Last 5: 3/5
Last 5: 1/5

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Open 7:40 pm EDT Tuesday, September 22, 2026

Chicago Cubs is favored -218. Total is 6.5.

Last 5: 2/5
Last 5: 3/5

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Open 8:05 pm EDT Tuesday, September 22, 2026

Texas Rangers is favored -149. Total is 7.5.

Last 5: 2/5
Last 5: 3/5

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Open 8:40 pm EDT Tuesday, September 22, 2026

Arizona Diamondbacks is favored -198. Total is 11.

Last 5: 2/5
Last 5: 1/5

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Open 9:40 pm EDT Tuesday, September 22, 2026

Seattle Mariners is favored -149. Total is 7.5.

Last 5: 1/5
Last 5: 3/5

Open 9:40 pm EDT Tuesday, September 22, 2026

Los Angeles Angels is favored -109. Total is 9.5.

Last 5: 2/5
Last 5: /5

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Open 9:45 pm EDT Tuesday, September 22, 2026

Minnesota Twins is favored -131. Total is 7.5.

Last 5: 2/5
Last 5: 2/5

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Open 10:10 pm EDT Tuesday, September 22, 2026

Los Angeles Dodgers is favored -120. Total is 8.

Last 5: 5/5
Last 5: 4/5

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