Indianapolis Colts vs Jacksonville Jaguars Picks and Predictions

Indianapolis Colts vs Jacksonville Jaguars Best Betting Picks

Indianapolis Colts
Line: -2.5 Total: o45.5 Score: 0

Jacksonville Jaguars
Line: +2.5 Total: u45.5 Score: 0

Make your bets before 1:00pm EST 12/7/2025

Best Bets for the Indianapolis Colts vs Jacksonville Jaguars

Below are the top 5 sports handicappers with picks on this game. Experts are listed in order based based on their hit rate from previous picks on the Indianapolis Colts and/or Jacksonville Jaguars games and their overall NFL rankings. Visit their website directly to purchase their best bets for the day.

Rank	Sports Handicapper	30 Day NFL Record	NFL Season Record	Hit Rate	Website
#1	Trevor J. Bass	22-9 (71%), +$6,095	59-27 (69%), +$14,940	33%	View Website
#2	Mathew Balance	21-16 (57%), +$1,895	78-47 (62%), +$13,890	0%	View Website
#3	"Slick" Rick Williams	17-13 (57%), +$1,530	59-32 (65%), +$12,110	0%	View Website
#4	Ryan Bowland	21-12 (64%), +$4,050	66-43 (61%), +$9,810	0%	View Website
#5	Alex "Jedi" Knight	20-10 (67%), +$4,630	50-29 (63%), +$9,580	60%	View Website

Vegas Trends and Betting Odds

Indianapolis Colts have won the past 2 out of 5 games (3 of 5 ATS) while the Jacksonville Jaguars have won the past 4 out of 5 games (3 of 5 ATS). The Indianapolis Colts are 2 and 3 on the most recent away games while the Jacksonville Jaguars are 3 and 2 at home. Vegas has the line at Indianapolis Colts -2.5 and the total at 45.5.

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